[Research] A study shows that Thiamidol, a new ingredient for hyperpigmentation / skin lightening, is much more effective than Hydroquinone, Kojic Acid and Arbutin, while being completely safe.

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Hi, I'm new here! Sorry if this is really long! I have hyperpigmentation on some areas of my body. I've been using Alpha Arbutin and Kojic acid twice a day for 6 months with no results, so I've been searching for something new. I came across Eucerin's new line of anti-pigment products, containing their patented skin lightening ingredient, Thiamidol. So, of course, I Googled Thiamidol. The only research I can find is this study. If you scroll all the way down to the "conflicts of interest" section, you'll see that out of the 10 scientists credited as authors, 8 of them are employees of Beiersdorf AG (which is the company that owns Eucerin). That obviously raises concerns about the validity of the research.Reading the study, it seems very interesting. Skin lightening chemicals work by inhibiting Tyrosinase, which is the chemical that makes you produce Melanin. So if you inhibit Tyrosinase, you won't produce as much Melanin, so your skin will get lighter. The authors say that in the past, dermatological scientists have extracted Tyrosinase from mushrooms to test their products on, but that's not great because mushroom Tyrosinase and human Tyrosinase are quite different. They say that they replicated human Tyrosinase, and tested 50,000 chemicals on it, including the go-to skin lightening ingredients Arbutin, Kojic acid, and the infamous Hydroquinone. Of course, they tested their own product (Thiamidol) on it too. They found that while Hydroquinone, Kojic Acid and Arbutin worked very well on mushroom Tyrosinase, they actually didn't work well on human Tyrosinase. Conversely, Thiamidol didn't work well on mushroom Tyrosinase, but worked very well on human Tyrosinase. They said Thiamidol worked the best out of the 50,000 chemicals they tested.They also did a clinical study, where they compared a cream containing 0.2% Thiamidol, and a placebo cream (all the same ingredients as the first cream, just without the Thiamidol) used twice daily on age spots. It says after 4 weeks, the spots that were treated with Thiamidol were significantly lighter, and after 12 weeks, they were indistinguishable from the surrounding 'normal' skin. While the placebo formula showed no change at all. Here's the before and after photo from the study. The study also says that Thiamidol "is not converted to a toxic and potentially leukoderma-inducing quinone", like Hydroquinone and Rhododendrol, so there's no safety concerns.But as awesome as this all sounds, the fact that the study was performed by the company itself obviously raises huge concerns about objectivity, bias etc. But considering the cream is only £15 ($19), there are no safety concerns, and the other products I've tried haven't worked, I just thought "why not?", so I bought it and started using it last night. It went on nicely, didn't leave a greasy/sticky film, had no smell and didn't cause any irritation. I'll be using it twice daily for the next few months, and if anyone's interested, I'll update with my progress.I'd be really interested to hear your thoughts on this study!
Girls Blog 2015
Submitted by GlandLocks