Monday, 26 June 2017

[Anti-Aging] What are your experiences with "Botox alternatives"?

Beauty Tips For Body Care
Argireline, Syn-Ake, and their ilk - what have been your experiences with ingredients that claim to inhibit muscle movements and smooth out wrinkles?The creators of Argireline describe the peptide as being "The first hexapeptide that is a replica of the N-terminal end of SNAP-25 and competes in vitro with the natural protein for a position in the SNARE complex.". This is comparable to Botox's mechanism, which also acts on SNAP-25 and prevents neurotransmitter release. The idea is that Argireline will prevent muscle contractions that cause skin wrinkling. Syn-Ake is a replica of a peptide from the temple viper snake (Waglerin 1), which also interferes with neurotransmission.I'm particularly curious about Argireline products, and I'm considering The Ordinary's 10% Argireline Solution as it's not a huge investment. I believe TO's Buffet also contains some Argireline and some Syn-Ake, but I'm not sure of the concentrations.I've heard concerns that these ingredients can cause skin sagging in the long term if you apply them all over the face. I've also heard of some people claiming these gave them "brain fog" as a side effect. I'm not a chemist, so I'm not sure of the validity behind the claim that a peptide could enter your system and affect your cognitive functioning.I'd love to hear anyone's thoughts on these products - have they worked well for you, or have they had zero effect? Do you feel they compare to Botox? Did you notice any side effects? Should we all stick to retinoids, sunscreen, and Frownies instead?
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Submitted by paisleypunk

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