[Anti-Aging] Melatonin on skin for wrinkles?

Beauty Tips For Body Care
Does anyone here use topical liposomal melatonin on their skin? I do. After reading up on it, I began using a 5mg liquid solution (per 1ml) on my face a week ago.Interestingly, the research shows it can reduce wrinkles rather fast (albeit in different melatonin solutions).There seems to be a dearth of information of any real life reports of this, even though one study showed fairly remarkable results after 12 weeks of use: See here: https://www.dovepress.com/antiaging-efficacy-of-melatonin-based-day-and-night-creams-a-randomize-peer-reviewed-fulltext-article-CCIDResults: All the subjects completed the study. Crow’s feet was reduced significantly (p=0.05) by –15% with the creams in comparison with the non-treated side after 3 months. At the end of the study, surface microrelief (–26.5%), skin profilometry (–13%), skin tonicity (+30%) and skin dryness (–59.5%) significantly improved with active treatment. Both products were well tolerated.Conclusion: In women with skin aging, Mel-based creams improved significantly skin tonicity and skin hydration with a significant reduction in skin roughness, supporting the skin antiaging effect of this molecule applied topicallyAnd here: https://www.mdpi.com/2079-9284/5/4/60/htmANTERA 3D evaluations showed a significant reduction in the coarse and fine wrinkle volume in the target area of −31% and −18%, respectively.And here: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583885/Thus, there is considerable evidence for melatonin to be an effective anti-skin aging compound, and its various properties in this context are described in this review.And here: https://link.springer.com/article/10.1007/s13555-020-00443-2Night Cream significantly reduced oxidative stress in human skin ex vivo. Clinically, hydration (+ 64.4%; p <� 0.05) and transepidermal water loss (TEWL) values (− 10.0%; p <� 0.05) were improved within 1 h of use. *****Wrinkle counts were reduced by up to 18.9% (*****p <� 0.05), and brown and UV spot numbers by 5.5% (p <� 0.05) and 13.2% (p <� 0.05), respectively. Lactic acid-induced stinging was significantly reduced within 7 days of use, with 86.7% of subjects reporting that their skin felt calmer.I know some people are worried it will make people sleepy, but the reading I have done shows that while it may affect the blood levels, it does not induce the same response transdermally as oral melatonin.
Girls Blog 2015
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