Sunday, 24 March 2019

[Skin Concerns] The Oily Skin HG Thread: Share your skincare secrets! (Week 4)

Beauty Tips For Body Care
Hi there and welcome to the Oily Skin HG thread!This is the place to discuss your favorite products for oily skin - whether it's the best oil-reducing toner, the greatest exfoliant, or the lightest non-greasy SPF moisturizer. Helpful habits and makeup recommendations are also welcome!Share your secrets with others and help them improve their skin! Don't forget to include as much info as you can: price range, product feel, what country you're in, whether the product is cruelty free/vegan/fragrance free, etc. It'll all be helpful to people reading this thread :)Thanks for contributing!This thread is part of a larger series of Skin Concerns HG threads. To see all scheduled threads, go here.Join us next week to talk about your favorite products for hyperpigmentation!
Girls Blog 2015
Submitted by AutoModerator

[misc] Hydrogen peroxide completely faded my self tanner. Good to know for accidental oompa loompa hands.

Beauty Tips For Body Care
https://i.redd.it/ddeg3xa9j5o21.jpg
Girls Blog 2015
Submitted by JewelWitch

[RESEARCH] New Tretinoin LOTION formulation, new acne treatments

Beauty Tips For Body Care
This information has been taken from Medscape and requires an account to access. I'm going to summarize below some key information from the presentation. I hope people find this interesting and become more up-to-date with recent advances in dermatology.​New Topical Retinoid - Tretinoin 0.05% Lotion ( https://www.rxlist.com/altreno-drug.htm, https://ir.bauschhealth.com/news-releases/2018/10-30-2018-120452296 )Two phase 3 studies (N=1640), patients with moderate to severe acne, age 9-58 yearsEvaluated efficacy, safety, and tolerability of tretinoin 0.05% lotion vs vehicleInflammatory and non-inflammatory lesion counts and acne severity evaluatedStatistically significant results in a cosmetically more elegant formula (!), effective for inflammatory and non-inflammatory lesions, reducing acne severityInactive ingredients: benzyl alcohol, butylated hydroxytoluene, carbomer copolymer type B (Pemulen TR-1), carbomer homopolymer type A (Carbopol 981), glycerin, methylparaben, mineral oil, octoxynol-9, purified water, sodium hyaluronate, soluble collagen and trolamine.​New topical antibiotic - 4% Minocycline foam ( https://www.sciencedirect.com/science/article/pii/S0190962218324745?via%3Dihub )2 identical phase 3 trials examined topical minocycline 4% foam in patients with moderate to severe acne (N=961)Patients were randomized 2:1 to once daily minocycline 4% foam vs vehicle for 12 weeksCoprimary endpoints = change in inflammatory lesion count compared to baselineTreatment success measured by an IGA of 0 or 1/clear or almost clear with a >2-grade improvement at week 12Monocycline-treated patients has significantly greater reduction in inflammatory lesions from baselinePossible replacement for systemic antibiotics?​Completely New Retinoid - Trifarotene 50mcg/g Cream ( https://onlinelibrary.wiley.com/doi/full/10.1111/bjd.16733 )Efficacy of trifarotene in patients moderate with facial and truncal acne vulgaris as assessed by the IGA (face) and PGA (trunk - meaning chest and back (!) )2 parallel multicenter trials in patients age >9 (N=1200)Significant difference in IGA and PGA in patients who received trifarotene vs placebo, P<.001​New Topical Anti-Androgen - Clascoterone 1% Cream ( https://sci-hub.tw/https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1365-2133.2011.10332.x )Androgen antagonist, competes with androgen receptor3x more potent than flutamide, 2x more than finasteride, equal to cyproterone acetateHas been shown to limit sebum production in vitro and down regulate proinflammatory cytokinesAt week 12, significant benefit compared with vehicle in IGA treatment success (clear, almost clear), non-inflammatory lesion counts (absolute reduction), inflammatory lesion counts (absolute reduction)​New Oral Antibiotic - Sarecycline ( https://www.drugbank.ca/drugs/DB12035 )Tetracycline-classAnti-inflammatory properties and narrower spectrum of activityApproved in Oct 2018 in patients > age 9, patients with moderate-severe facial acne, weight based dosing 1.5mg/kg/day, once daily with or without foodEndpoint: >2-grade improvement in IGA and clear/almost clearAt week 12, for facial acne, IGA success, inflammatory lesion reduction; for truncal acne, IGA success for chest and backNo vertigo or tinnitus TEAEs, minor increase in dizziness AEs, sunburn and photosensitivity were uncommon, low rates of vaginal yeast infections typically associated with oral antibiotics in female subjectsEffective at 3 weeks (!)​TLDR: A hopeful new tretinoin formulation in a more tolerable vehicle, new topical and oral antibiotics with fast results, entirely new retinoid aimed at treating chest and back acne.
Girls Blog 2015
Submitted by silverkeith

[personal] Got told my skin was glowing - on a day I felt miserable and barfy (migraine) - so I think it was my skincare routine starting to improve my skin!!

Beauty Tips For Body Care
AM:bioderma pink cap, CosRx snail mucin essence, TO rosehip oilPM: same as AM
Girls Blog 2015
Submitted by accioletter

[DIY] Stained for today but hydrated for weeks

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https://i.redd.it/ume2zzu1w4o21.jpg
Girls Blog 2015
Submitted by SuperGirl15

[SKIN CONCERNS] Does anyone know what these flakes are called and how to remove them? Hard to see a dermatologist in Canada. Around sides of nose, chin and upper lip area.

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https://i.redd.it/1vmmjibs04o21.jpg
Girls Blog 2015
Submitted by RainbowMonkeyy

[misc] Ruined armpits

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I realized today that I have destroyed my armpits. I know this will probably be jerked but I am serious and actually upset.All the hair removal and then drying the shit out of them with deo has made the skin there so wrinkly, dry and thin...I usually pay a lot of attention to my whole body but for some reason I never gave much thought to armpits, just put some deo on and call it a day.I spent my Sunday with baby oil and Lanolin on them. Probably ruined my shirt, but I feel so guilty.I want to remind everyone to take care of your armpits...
Girls Blog 2015
Submitted by doeatmypoop